Mesterolone-25mg is a synthetic androgen drug with strong efficacy but hidden risks, with mesterolone as its core ingredient. Compared with the 10mg specification, the high dose of 25mg makes it show more significant effects in the treatment of men’s diseases, but it is also accompanied by a higher threshold for use and health risks.
From the perspective of drug properties, the unique chemical structure gives it good oral activity and is not easily metabolized by the liver. After entering the human body, it can quickly bind to androgen receptors and strongly regulate gene expression. Whether it is promoting protein synthesis, enhancing muscle strength, stimulating red blood cell production, improving endurance, or regulating reproductive endocrine, its intensity and duration of action are far superior to the low-dose version, and it can be called a “powerful weapon” for the treatment of men’s diseases.
In clinical applications, it is specially designed for patients with severe androgen deficiency. For men with congenital agenesis or testicular loss, it can quickly supplement androgen, effectively improve sexual function, and rebuild muscles and physical fitness; for patients with refractory oligospermia and asthenospermia who do not respond to conventional treatments, it can deeply regulate reproductive endocrine system and significantly improve sperm quality; in terms of alleviating the symptoms of severe androgen deficiency in middle-aged and elderly men, it can also significantly improve their sexual function, physical activity and mental state.
Mesterolone-25mg Product Introduction
The core ingredient of Mesterolone-25mg is also mesterolone (1α-methyl-dihydrotestosterone). As a synthetic androgen drug, its single-tablet dosage is higher than that of 10mg, and it shows stronger efficacy in the treatment of male diseases and the improvement of male health, but it is also accompanied by higher medication risks and stricter usage specifications.
I. Basic characteristics
(I) Composition and structure
The chemical formula of mesterolone C₂₀H₃₂O determines its androgenic properties. The presence of 1α-methyl gives it good oral activity and low liver metabolic sensitivity. The high dose of 25mg means that the amount of mesterolone entering the human body per unit time is greatly increased, and the drug binds to the androgen receptor more quickly and tightly, which significantly increases the intensity and duration of androgenic effects, but also aggravates the impact on the body’s endocrine, metabolic and other systems.
(II) Dosage form and specifications
It is commonly a white oral tablet, each tablet contains exactly 25mg mesterolone. The large-dose single-tablet design reduces the number of tablets taken per day, making it more convenient for experienced patients or those who need a larger dose of treatment, but it also places higher requirements on dosage control. The packaging specifications are mostly 30 tablets/box, and the storage conditions are the same as the 10mg specifications. It needs to be kept away from light, sealed, and stored in a cool and dry place to prevent the drug from deteriorating.
(III) Mechanism of action
After entering the human body, the mesterolone in Mesterolone-25mg quickly binds to the androgen receptor to form a complex, which strongly regulates gene expression. Compared with the 10mg specification, it can more efficiently promote protein synthesis, accelerate the uptake of amino acids by muscle cells, and significantly improve muscle mass and strength; it has a stronger stimulating effect on erythrocyte production, can more quickly increase hemoglobin levels, and enhance the body’s oxygen carrying capacity; in terms of the reproductive system, it has a stronger regulatory effect on the hypothalamus-pituitary-gonadal axis, and the effect of promoting sperm production is more prominent, but it may also cause more obvious endocrine fluctuations.
II. Clinical application
(I) Treatment of severe male hypogonadism
Applicable population: Suitable for male patients with severe androgen deficiency, such as congenital anorchia, complete loss of testicular function, etc. Such patients have severe symptoms, manifested as significant loss of sexual desire, complete erectile dysfunction, severe muscle atrophy and physical decline.
Therapeutic effect: High doses of Mesterolone-25mg can quickly replenish androgens in the body, effectively improve the patient’s sexual function, restore sexual desire and erectile ability; promote muscle synthesis, increase muscle mass, improve physical weakness; regulate metabolism, relieve fatigue, and improve quality of life. Some patients can see significant improvement in physical and mental state after taking the medicine for several weeks.
Usage: The recommended initial dose is 50-75mg per day, taken orally in 1-2 times. The doctor will adjust the dose every 2-4 weeks according to the patient’s testosterone level and symptom improvement, and the maintenance dose is generally around 50mg per day. During treatment, testosterone, liver function, blood lipids, prostate-specific antigen (PSA) and other indicators need to be closely monitored to ensure that the treatment is safe and effective.
(II) Auxiliary treatment of refractory oligospermia and asthenospermia
Applicable population: Male infertile patients with poor results from conventional treatment and severely low sperm quality. Such patients may have complex reproductive endocrine disorders, and low-dose androgen therapy alone is not effective.
Therapeutic effect: Mesterolone-25mg can more effectively regulate the reproductive endocrine environment, promote the development of testicular spermatogenic cells and sperm maturation, and increase sperm count and vitality. Clinical studies have shown that after continuous use for 3-6 months, the semen quality of some refractory patients can be significantly improved, and some patients have successfully achieved natural conception.
Usage: The dose is usually 50-75mg per day, taken orally 1-2 times. During the treatment process, it is necessary to regularly review semen routine, six sex hormones and other indicators, and adjust the treatment plan in time according to the examination results. At the same time, combined with other spermatogenic drugs and nutritional supplements, the therapeutic effect can be enhanced.
(III) Relieve the symptoms of severe androgen deficiency in middle-aged and elderly men
Applicable population: It is suitable for middle-aged and elderly men with severe androgen deficiency symptoms that have greatly affected their quality of life, such as severe sexual dysfunction, severe muscle loss leading to difficulty in movement, obvious depression, etc.
Therapeutic effect: High-dose mesterolone can effectively relieve the patient’s severe symptoms, improve sexual desire and sexual function; increase muscle strength, improve physical activity; regulate emotions, relieve depression, and improve quality of life. However, it should be noted that the physical function of middle-aged and elderly patients has declined, and close attention should be paid to adverse reactions when taking the medicine.
Usage: The initial dose starts at 50mg per day, orally. During the medication, the patient’s reaction should be closely observed. If adverse reactions such as worsening symptoms of prostate hyperplasia and sleep apnea occur, the dose should be adjusted or the drug should be stopped immediately. At the same time, PSA levels should be monitored regularly to check for prostate cancer risks.
III. Dosage and Administration
(I) Individualized Precision Adjustment
The dosage of Mesterolone-25mg needs to be precisely adjusted according to the patient’s age, underlying disease, physical tolerance and other factors. Young patients in good physical condition can try higher doses after evaluation by a doctor; elderly patients or patients with cardiovascular disease, liver and kidney dysfunction need to start with a low dose and increase slowly, while strengthening the monitoring of various indicators.
(II) Strictly follow the doctor’s instructions
Patients must strictly follow the doctor’s prescription to take the medicine, and it is strictly forbidden to increase or decrease the dose or stop the medicine on their own. When used at high doses, even a slight change in the dose may affect the treatment effect or cause adverse reactions. If you feel uncomfortable during medication, you should seek medical attention immediately and adjust the treatment plan under the guidance of a doctor.
None of our HGH lines are inherently better than the other. Each batch comes with a corresponding test report. Purity and dimer can be a decent proxy for “quality”, you want purity as high as possible and dimer as low as possible. The main factor to consider in our opinion, is the price per IU. Supreme is usually the best bang for buck option. Historically, Supreme & Deluxe have shown lower dimer content, although this may not always be the case, so of course reference the corresponding test reports.
For HGH, we typically recommend 1ml for every ~10 IU in the vial. If a batch tests at an average of 290 IU per kit, that is an average of 29 IU per vial, and we’d recommend 2.9ml of bacteriostatic water. This will make the syringe math similar to a traditional 100 iu kit with 1ml of solution For peptide reconstituion, you can use our amazing Dosage Calculator.
Not necessarily. If you look through all our lab reports, particularly the ones with multiple test reports in a single batch, you will see that the intra-batch variance can actually be quite high. When you purchase a batch, you can expect some of the vials in your kit to be as much as 5-15% +/- whatever the corresponding lab test reflects. This is simply the reality of product that is not made to the same standards as pharmaceutical grade growth hormone. To state otherwise would be disingenous. There can also be a high variance in the dimer content intra-batch. (For Example: Economy B, Deluxe A, etc) Over time, we’ve increased the volume of samples analyzed for each batch, to provide more transparancy regarding the potential for intra-batch variance. If you use the average IU figure provided on each product, your dosage should average out over time, so don’t overthink your administration protocol too much. We know it can be a bit overwhelming with all the different numbers provided. That said, don’t hesitate to reach out if you need specific guidance on dosage or reconstitution.
Yes! We offer store credit for quantitative testing of total IU/Purity (ie Janoshik testing), and for personal IGF-1 test results. Please email for more information. *TERMS APPLY*
Depending on your location, most customers receive their order in 2-10 business days. We ship with USPS Ground Shipping, from the United States only. 99% of orders ship within 24 hours (excluding weekends & holidays)
We are no longer providing tracking. If your order is over 10 business days old and hasn’t arrived, our customer service team can check your tracking information to see the status of your package
If your order was marked as “completed”, typically this means a label has been generated and your order is scheduled to go out that day or the next. “Processing” status orders have not been shipped, processing means payment has been confirmed successfully. Don’t hesitate to reach out regarding the status of your order.
Unfortunately we do not provide reships for incorrect addresses. In the VERY rare instance that a package is lost in transit, we will reship your order free of charge.
From the composition point of view, Clenbuterol belongs to β₂-adrenaline receptor agonist. It binds to human receptors with its specific chemical structure, activates intracellular signaling pathways, promotes fat decomposition, dilates bronchi, and affects cardiovascular function. Medically, it was once an asthma treatment drug that can relieve dyspnea, but it has been gradually eliminated because it can cause serious cardiovascular side effects such as palpitations and arrhythmias; researchers have also tried to use it for the treatment of chronic obstructive pulmonary disease, but it is also hindered by side effects.
In the fitness and competitive sports world, Clenbuterol is regarded as a “powerful fat-reducing artifact” that can quickly accelerate fat decomposition, improve basal metabolism, and help fitness enthusiasts shape clear muscle lines in a short period of time; it can also enhance cardiopulmonary function and improve sports endurance, which has also led some athletes to take risks and use it in violation of regulations in pursuit of results.
Turinabol is a modified oral anabolic steroid combining the muscle-building properties of Dianabol with the low side effects of Primobolan. Each tablet contains 25mg of high-purity active compound, with 100 tablets per bottle (total 2500mg).
Turinabol is a modified oral anabolic steroid combining the muscle-building properties of Dianabol with the low side effects of Primobolan. Each tablet contains 25mg of high-purity active compound, with 100 tablets per bottle (total 2500mg).
ANAVAR-10mg Product Description
ANAVAR-10mg is an oral anabolic steroid product with Oxandrolone as the active ingredient. Each tablet contains 10mg of Oxandrolone and is usually presented as a white or off-white film-coated tablet. With its unique molecular structure and efficacy characteristics, it has attracted widespread attention in the medical and non-medical fields.
In medical use, ANAVAR-10mg is a powerful helper in the treatment of muscle wasting diseases. For HIV-related muscle atrophy, it can activate androgen receptors, accelerate protein synthesis, help patients restore muscle mass and physical strength, and improve weight loss caused by the disease; for children with Turner syndrome, it can help improve growth retardation under strict doctor supervision. At the same time, in the recovery stage after surgery or trauma, it can also play a role in promoting tissue repair and help patients recover their physical functions.
