GHRP-6 Kit
Price range: $32.00 through $55.00
(CAS 87616-84-0); supplier specifications (Zhuzhou New Peptides Tech, Wuhan Boyuan Import & Export); preclinical summaries on GH secretagogue mechanisms and metabolic regulation.
Description
🧪 Product Profile: GHRP-6
Product Name: GHRP-6 (Growth Hormone Releasing Peptide-6)
CAS Number: 87616-84-0
Molecular Formula: C₄₆H₅₆N₁₂O₆
Molecular Weight: 873.01 g/mol
Amino Acid Sequence: His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂
Purity: ≥98% (HPLC verified, premium grades up to 99.9% available)
Formulation: Lyophilized powder (standard vial sizes: 5mg, 10mg, 50mg; custom specifications available)
🔬 Key Characteristics
GHRP-6 is a synthetic hexapeptide belonging to the growth hormone secretagogue (GHS) family, designed to stimulate endogenous growth hormone (GH) release through activation of the growth hormone secretagogue receptor (GHS-R). Its structure features D-amino acid substitutions (D-Trp, D-Phe) that enhance metabolic stability and receptor affinity, distinguishing it from natural GH-releasing hormones.
⚙️ Mechanism of Action
- GH Secretion Stimulation: Binds to GHS-R in the anterior pituitary gland, triggering a dose-dependent increase in GH release by depolarizing somatotroph cells and enhancing calcium influx.
- Ghrelin Receptor Agonism: Acts as a functional agonist of the ghrelin receptor (GHS-R1a), regulating appetite, energy balance, and nutrient partitioning.
- IGF-1 Modulation: Indirectly increases insulin-like growth factor-1 (IGF-1) production via GH-dependent pathways, supporting anabolic processes and cellular growth.
- Metabolic Regulation: Promotes lipolysis (fat breakdown) while preserving lean muscle mass, with preclinical evidence suggesting improved insulin sensitivity in metabolic models.
📊 Research Applications
- Endocrinology: Studies on GH deficiency, pituitary function, and somatotropic axis regulation.
- Metabolic Research: Investigation of obesity, sarcopenia, and metabolic syndrome models.
- Sports Physiology: Preclinical evaluation of muscle growth, recovery, and performance enhancement mechanisms.
- Gerontology: Research on age-related GH decline and potential anti-aging interventions.
💡 Product Features
- Stability: Lyophilized form ensures long-term stability under -20°C storage; reconstitute with sterile solvent (e.g., bacteriostatic water) for laboratory use.
- Bioavailability: Rapid absorption and high receptor specificity in in vitro and animal models.
- Purity: Pharmaceutical-grade formulation (≥98% HPLC) with low endotoxin levels, suitable for cell culture and preclinical studies.
⚠️ Disclaimer
For Research Use Only: Not approved for human or veterinary clinical applications. Handling requires compliance with peptide research protocols, including proper storage, reconstitution, and biosafety measures.
Additional information
| FORMAT | 10Bottlex5mg, 10Bottlex10mg |
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