Dermorphin 5 mg*10vials Kit

$75.00

Description

🧪 Product Profile: Dermorphin

Product Name: Dermorphin
CAS Number: 77614-16-5
Category: Natural opioid peptide; research-grade neuroactive compound
Form: Lyophilized white powder in sealed glass vials
Molecular Formula: C₃₉H₅₄N₈O₉
Molecular Weight: 786.9 g/mol
Purity: ≥99% (HPLC verified)

🔬 Key Properties

  • Amino Acid Sequence: H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH₂ (contains unusual D-alanine residue)
  • Solubility: ≥25 mg/mL in TBS buffer (0.5M Tris-HCl, pH7.4 with 1M NaCl)
  • Storage Stability:
    • Lyophilized form: 2-8°C for 24 months (desiccated, protected from light)
    • Reconstituted solution: Use within 48 hours when stored at 2-8°C
  • Physical Characteristics: Amorphous powder; endotoxin level ≤0.1 EU/mg

🧠 Mechanism of Action

Dermorphin acts as a highly selective μ-opioid receptor (MOR) agonist with:

  • Binding Affinity: ~30-40 times greater potency than morphine at MOR
  • Analgesic Pathway: Inhibits nociceptive signaling by reducing neuronal放电 in the lateral thalamic nuclei and spinal dorsal horn
  • Unique Structure: D-alanine residue enhances resistance to enzymatic degradation, prolonging in vivo half-life
  • Modulatory Effects: Suppresses C-fiber mediated pain responses in rodent models (1.9 µmol/kg, i.p.)

🧪 Research Applications

Primarily investigated in preclinical pain and neuroscience studies:

  • Neuralgia Models: Treatment of chronic neuropathic pain and inflammatory hyperalgesia
  • Opioid Receptor Pharmacology: MOR subtype selectivity assays and ligand binding studies
  • Peptide Biosynthesis: Investigation of post-translational D-amino acid isomerization in amphibian skin glands
  • Drug Development: Lead compound for designing novel analgesics with reduced addiction potential

⚙️ Handling & Administration

  • Reconstitution: Dissolve in 1× TBS buffer or sterile saline to desired concentration (typically 1-10 mg/mL)
  • Administration Routes: Intracerebroventricular (ICV), intraperitoneal (i.p.), or subcutaneous injection in animal models
  • Dosing Considerations:
    • Rodent studies: 0.1-5 µmol/kg for analgesic effect evaluation
    • In vitro assays: 10-100 nM for receptor binding experiments

📦 Supplier Specifications

  • Packaging Options: 2mg/vial, 5mg/vial, 10mg/vial, or custom sizes
  • Minimum Order: 1 vial (research quantities) to 100kg (bulk)
  • Delivery: Discreet packaging with multiple shipping options (EMS/DHL/FedEx); ~7-day delivery time

⚠️ Safety & Regulatory Status

  • Research Use Only (RUO): Not approved for human or veterinary clinical use
  • Toxicity Profile: Potential for respiratory depression and central nervous system depression at high doses
  • Legal Status: Classified as a controlled substance analog in some jurisdictions due to opioid activity
  • Handling Precautions: Requires PPE (gloves, lab coat) and secure storage in controlled-access facilities

Frequently Asked Questions

USP Grade MCT oil is the carrier oil. The only solvents used are Benzyl Alcohol & Benzyl Benzoate (BA & BB).
None of our HGH lines are inherently better than the other. Each batch comes with a corresponding test report. Purity and dimer can be a decent proxy for “quality”, you want purity as high as possible and dimer as low as possible. The main factor to consider in our opinion, is the price per IU. Supreme is usually the best bang for buck option. Historically, Supreme & Deluxe have shown lower dimer content, although this may not always be the case, so of course reference the corresponding test reports.
For HGH, we typically recommend 1ml for every ~10 IU in the vial. If a batch tests at an average of 290 IU per kit, that is an average of 29 IU per vial, and we’d recommend 2.9ml of bacteriostatic water. This will make the syringe math similar to a traditional 100 iu kit with 1ml of solution For peptide reconstituion, you can use our amazing Dosage Calculator.
No, you must purchase it seperately .
Not necessarily. If you look through all our lab reports, particularly the ones with multiple test reports in a single batch, you will see that the intra-batch variance can actually be quite high. When you purchase a batch, you can expect some of the vials in your kit to be as much as 5-15% +/- whatever the corresponding lab test reflects. This is simply the reality of product that is not made to the same standards as pharmaceutical grade growth hormone. To state otherwise would be disingenous. There can also be a high variance in the dimer content intra-batch. (For Example: Economy B, Deluxe A, etc) Over time, we’ve increased the volume of samples analyzed for each batch, to provide more transparancy regarding the potential for intra-batch variance. If you use the average IU figure provided on each product, your dosage should average out over time, so don’t overthink your administration protocol too much. We know it can be a bit overwhelming with all the different numbers provided. That said, don’t hesitate to reach out if you need specific guidance on dosage or reconstitution.
Yes! We offer store credit for quantitative testing of total IU/Purity (ie Janoshik testing), and for personal IGF-1 test results. Please email for more information. *TERMS APPLY*
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Depending on your location, most customers receive their order in 2-10 business days. We ship with USPS Ground Shipping, from the United States only. 99% of orders ship within 24 hours (excluding weekends & holidays)
We are no longer providing tracking. If your order is over 10 business days old and hasn’t arrived, our customer service team can check your tracking information to see the status of your package
If your order was marked as “completed”, typically this means a label has been generated and your order is scheduled to go out that day or the next. “Processing” status orders have not been shipped, processing means payment has been confirmed successfully. Don’t hesitate to reach out regarding the status of your order.
Unfortunately we do not provide reships for incorrect addresses. In the VERY rare instance that a package is lost in transit, we will reship your order free of charge.
Yes. If you need more information or have a specific request, please email us.
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