Semax Kit
Price range: $50.00 through $70.00
(CAS 80714-61-0); supplier product specifications (MOLCOO, 固拓生物); preclinical summaries on neurotrophic activation and cognitive enhancement mechanisms.
Description
🧪 Product Profile: Semax
Product Name: Semax
CAS Number: 80714-61-0
Molecular Formula: C₃₇H₅₁N₉O₁₀S
Amino Acid Sequence: H-Met-Glu-His-Phe-Pro-Gly-Pro-OH (Met-Glu-His-Phe-Pro-Gly-Pro)
Purity: ≥98% (HPLC verified, some suppliers offer ≥99% purity grades)
Formulation: Lyophilized powder (typically available in 5mg, 10mg, or custom vials)
🔬 Key Characteristics
Semax is a synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH), specifically the ACTH (4-10) sequence with a methionine extension. It exhibits high blood-brain barrier permeability and acts as a multifunctional neuroregulator, combining cognitive-enhancing, neuroprotective, and mood-stabilizing properties in preclinical research.
⚙️ Mechanism of Action
- Neurotransmitter Modulation: Regulates monoamine neurotransmitters (dopamine, norepinephrine, serotonin) to enhance synaptic plasticity and cognitive function, while supporting mood balance through GABAergic system interactions.
- Neurotrophic Activation: Stimulates transcription of neurotrophic factors (e.g., BDNF), promoting neuronal survival, dendrite growth, and repair mechanisms in models of brain injury or neurodegeneration.
- Anti-Inflammatory Effects: Mitigates neuroinflammation by inhibiting pro-inflammatory cytokine release, contributing to its neuroprotective profile in ischemic or traumatic brain injury models.
📊 Research Applications
- Cognitive Neuroscience: Studies on memory enhancement, attention span, and learning capacity in aging or cognitive impairment models.
- Neuroprotection: Investigation of therapeutic potential in stroke, traumatic brain injury, and neurodegenerative disease research (e.g., Alzheimer’s, Parkinson’s).
- Psychopharmacology: Evaluation of anxiolytic and mood-regulating effects in stress and anxiety disorder models.
💡 Product Features
- Stability: Lyophilized form ensures long-term stability under recommended storage conditions (-20°C to -80°C, protected from light).
- Reconstitution: Requires sterile solvent (e.g., bacteriostatic water) for laboratory use; exhibits good solubility in aqueous solutions.
- Purity: High-grade formulation with ≥98% HPLC purity, suitable for in vitro and preclinical research applications.
⚠️ Disclaimer
For Research Use Only: Not approved for human or veterinary clinical applications. Handling requires adherence to standard peptide research protocols, including proper PPE and biosafety measures.
Additional information
| FORMAT | 10Bottlex5mg, 10Bottlex11mg |
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